EST Lab – EST-Lab.com

Services

EST offers a wide array of services. Contact us if you have questions regarding these services.

  • Dialysis of Semipermeable Membrane Device (SPMD)
  • Quality Control (QC) Spiking
  • PRC (Permeability Reference Compound) spiking is done to gauge the effects of turbulence, temperature and biofouling on the uptake rates of the hydrophobic compounds. Spiking can also be done during various points in the dialysis and clean up procedure to monitor the process. To date, the POCIS can not be spiked with PRC
  • Gel Permeation Chromatography (GPC) cleanup
  • Extraction of Polar Organic Chemical Integrative Sampler (POCIS)
  • Custom quotes and estimated shipping if postal code is provided

Common Toxins found with SPMD

The compounds below are the common contaminates sampled by SPMDs. Many other hydrophobic substances with a logKow greater than 3.0 can be sequestered in triolein and ultimately analyzed.

Acronym Name Possible Source
PAH Polycyclic Aromatic Hydrocarbons Combustion by-product
OC Organochlorines Pesticide
PCB Polychlorinated Biphenyls Industrial and electrical
Pyrethroids Insecticide
Dioxins Combustion, industrial
Furans Industrial by-product
Nonyl Phenols Industrial
Alkylated Selenide Fossil fuels
PBDE Polybrominated Diphenyl Ethers Polybrominated Diphenyl Ethers

Common contaminates found with POCIS

Compound Class Example
AnalgesicsIbuprofen
AntibioticsOxytetracycline
Anti-ConvulsantsEthotoin
Mephenytoin
Anti-DepressantsPhenelzine
DecongestantsEphedrine acetate
FragrancesGalaxolide (HHCB) and Tonalide (AHTN)
HerbicidesAtrazine
Hormones17 α-ethynyestradiol
Estrogen
StimulantsCaffeine
Sulfa drugsSulfadiazine
Sulfamerizine
SurfactantsNonyl-phenol
VitaminsNicotinic Acid
Illicit drugsMethamphetamine

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